3 Ways to use Niacinamide

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Reflecting on these notable clinical considerations, we begin to understand just how relevant, powerful and versatile focused niacinamide supplementation can be.

Difference between Niacin and Niacinamide?

The two principal forms of the water soluble vitamin B3, include niacin and its amide form niacinamide. While niacinamide and niacin can both prevent the development of a B3 deficiency, they have very different pharmacological activities within the body and therefore demonstrate unique clinical considerations.

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References

Chen, A, Martin, A, Choy, B, Fernández-Peñas, P, Dalziell, R, McKenzie, C, Scolyer, R, Dhillon, H, Vardy, J, Kricker, A, George, G, Chinniah, N, Halliday, G & Damian, D 2015, ‘A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention’, New England Journal of Medicine, Vol. 373, No.17, pp. 1618-26.

Prousky, J 2005, ‘Supplemental Niacinamide Mitigates Anxiety Symptoms: Three Case Reports’, Journal of Orthomolecular Medicine, Vol. 20, No. 3, pp. 167-78.

Cantó, C, Menzies, K & Auwerx, J 2015, ‘NAD+ metabolism and the control of energy homeostasis – a balancing act between mitochondria and the nucleus’, Cell metabolism, vol. 22, pp. 1, pp. 31-53.