Summary

  • Enterosgel reduces blood toxicity and blood sugar levels in the presence of a kidney infection alongside diabetes mellitus.


Abstract

Background: 

Prior to clinical studies, experimental studies with the aim of studying the influence of Enterosgel, Polisorb MP and activated carbon on adsorption of microorganism in test culture.

Methods: 

A comparative analysis of clinical count and biochemical tests of blood and urine of patients with purulent pyelonephritis in combination with diabetes mellitus was conducted. The main group of 26 individuals received 22 g of Enterosgel half an hour before a meal to reduce endogenous toxicosis and decrease blood sugar level; the control group of 26 individuals received traditional therapy.

Results: 
In vitro observation revealed that Enterosgel and activated carbon actively adsorb E. Coli, while Polisorb MP adsorbs it even quicker. The study of adsorption of sugar by Enterosgel, Polisorb MP and activated carbon performed with 5% sugar solution showed that Enterosgel extracted more than a half of glucose from the original solution in three hours; activated carbon and Polisorb MP do not have this sugar adsorption property.
Conclusions: 

Based on all experimental testing we concluded that Enterosgel may be prescribed as a part of comprehensive therapy of severe forms of purulent pyelonephritis in combination with diabetes mellitus. Analysis of the therapy provides evidence that comprehensive treatment of purulent pyelonephritis with diabetes mellitus with the support of Enterosgel contributes to mitigation of direct toxic impact on the glomerulotubular kidney apparatus and improves kidney blood circulation due to normalization of rheological blood properties. The proof is the improvement in endotoxemia and homeostasis.

In this regard, it must be emphasized that Enterosgel normalizes blood glucose, is directly involved in the regulation of blood sugar, which helps to reduce the complications of diabetes. This is evidenced by the data on the dynamics of sugar, the improvement of glomerular function and the normalization of immunity indicators.

Source: https://umj.usma.ru/jour/article/view/636